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msc osteogenic differentiation medium  (PromoCell)


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    PromoCell msc osteogenic differentiation medium
    Msc Osteogenic Differentiation Medium, supplied by PromoCell, used in various techniques. Bioz Stars score: 95/100, based on 118 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/msc osteogenic differentiation medium/product/PromoCell
    Average 95 stars, based on 118 article reviews
    msc osteogenic differentiation medium - by Bioz Stars, 2026-02
    95/100 stars

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    Schematic conceptualization of this study. IR activated the NF-κB signaling pathway to promote activation and maturation of DCs, amplifying inflammatory signals through the release of pro-inflammatory cytokines. The mDCs triggered oxidative stress of BMSCs, showing increased intracellular ROS levels, inhibited <t>osteogenic</t> differentiation, and enhanced adipogenic differentiation, which accelerated the progression of radiation-induced jaw injury. VitD3-induced tolDCs exhibited IR resistance and anti-inflammatory properties, possessing the therapeutic potential to accelerate bone regeneration in irradiated jaw defects through local administration. (IR: ionizing radiation; mDC: mature dendritic cell; tolDC: tolerogenic dendritic cell; BMSC: bone marrow <t>mesenchymal</t> stem cell; ROS: reactive oxygen species; vitamin D3: vitD3)
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    Multi-lineage differentiation potential of dental follicle stem cells (DFSCs). Control cells (A and C) compared to <t>osteogenic</t> induction of DFSCs under alizarin red stain with calcium deposition (black arrow) (B) and adipogenic induction of DFSCs under oil red-O stain with lipid droplet accumulation (black arrow) (D). Scale bars, 50 μm.
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    Schematic conceptualization of this study. IR activated the NF-κB signaling pathway to promote activation and maturation of DCs, amplifying inflammatory signals through the release of pro-inflammatory cytokines. The mDCs triggered oxidative stress of BMSCs, showing increased intracellular ROS levels, inhibited osteogenic differentiation, and enhanced adipogenic differentiation, which accelerated the progression of radiation-induced jaw injury. VitD3-induced tolDCs exhibited IR resistance and anti-inflammatory properties, possessing the therapeutic potential to accelerate bone regeneration in irradiated jaw defects through local administration. (IR: ionizing radiation; mDC: mature dendritic cell; tolDC: tolerogenic dendritic cell; BMSC: bone marrow mesenchymal stem cell; ROS: reactive oxygen species; vitamin D3: vitD3)

    Journal: Stem Cell Research & Therapy

    Article Title: Ionizing radiation-mediated dendritic cell maturation exacerbates inflammatory response of bone marrow mesenchymal stem cells and impairs osteogenesis in radiation-induced jaw injury

    doi: 10.1186/s13287-025-04508-x

    Figure Lengend Snippet: Schematic conceptualization of this study. IR activated the NF-κB signaling pathway to promote activation and maturation of DCs, amplifying inflammatory signals through the release of pro-inflammatory cytokines. The mDCs triggered oxidative stress of BMSCs, showing increased intracellular ROS levels, inhibited osteogenic differentiation, and enhanced adipogenic differentiation, which accelerated the progression of radiation-induced jaw injury. VitD3-induced tolDCs exhibited IR resistance and anti-inflammatory properties, possessing the therapeutic potential to accelerate bone regeneration in irradiated jaw defects through local administration. (IR: ionizing radiation; mDC: mature dendritic cell; tolDC: tolerogenic dendritic cell; BMSC: bone marrow mesenchymal stem cell; ROS: reactive oxygen species; vitamin D3: vitD3)

    Article Snippet: BMSCs were co-cultured with mDC-CM and OriCell SD rat bone marrow mesenchymal stem cell osteogenic differentiation basal medium (Cyagen, USA).

    Techniques: Activation Assay, Irradiation

    Multi-lineage differentiation potential of dental follicle stem cells (DFSCs). Control cells (A and C) compared to osteogenic induction of DFSCs under alizarin red stain with calcium deposition (black arrow) (B) and adipogenic induction of DFSCs under oil red-O stain with lipid droplet accumulation (black arrow) (D). Scale bars, 50 μm.

    Journal: Journal of Dental Sciences

    Article Title: Induction of retinal progenitors and neurons from dental follicle stem cell under defined conditions

    doi: 10.1016/j.jds.2025.03.008

    Figure Lengend Snippet: Multi-lineage differentiation potential of dental follicle stem cells (DFSCs). Control cells (A and C) compared to osteogenic induction of DFSCs under alizarin red stain with calcium deposition (black arrow) (B) and adipogenic induction of DFSCs under oil red-O stain with lipid droplet accumulation (black arrow) (D). Scale bars, 50 μm.

    Article Snippet: DFSCs were seeded into 6-well at a density of 3 × 10 5 cells/well and stimulated with osteogenic induction medium (Human Mesenchymal Stem cell [hMSC] Osteogenic Differentiation Medium BulletKit) (Lonza, Basel, Switzerland).

    Techniques: Control, Staining